Abstract :
Bacterial multi-resistance is currently a major problem in our hospitals, because of the morbidity and mortality it generates mainly in intensive care and intensive care settings, and also a current medical problem. The objective of this study was to describe the epidemiological profile, frequency, and resistance status of bacteria resistant to Carbapenems at the Avicenne military hospital in Marrakech, over a period of 7 years from 2015 to 2021.
This is a retrospective descriptive study of all the highly resistant bacteria identified from the database of the microbiology department at the HMA in Marrakech. The results show that the general prevalence of these HRBs was 7.54%, with a clear predominance of Carbapenem-resistant Acinetobacter baumannii (53.4%), followed by Carbapenem-resistant Klebsiella pneumoniae (20.68%), then Carbapenem-resistant Enterobacter cloacae (9.57%), and finally Carbapenem-resistant Pseudomonas aeruginosa (6.17%).
The general evolution of isolated HRBs was marked by the gradual and continuous increase in the prevalence of these bacteria during the study period, with a peak in 2020, when the prevalence reached 13.98%.
High co-resistance has been found to several antibiotic molecules, which can be administered as an alternative.
The rationalization of the prescription of antibiotics and the rigorous application of hygiene and prevention rules will make it possible to limit the emergence of these multi and highly resistant bacteria in our care structures.
Knowledge of the bacteriological profiles and rates of resistance to antibiotics of this type of bacteria will allow treatment more adapted to each hospital context, and better targeted.