Abstract
Ganglioneuromas is usually arising in the posterior mediastinum and the retroperitoneum, but parapharyngeal ganglioneuromas are so rare that only 11 cases have been reported in the literature. We report a case of a 26-year-old woman with a parapharyngeal ganglioneuroma. who presented with a history of a indolent right cervical mass for 24 years. Computed tomography scan suggested that the mass was located between the carotid sheath and cervical vertebrae. The mass was completely resected under general anesthesia. It was a well-circumscribed, grayish-white and fish-shaped mass, 3.9 × 1.3 × 5.2 cm in size. Histological examination gave the diagnosis of ganglioneuroma, which was also confirmed by immunohistochemical stainings for Neuron-specific enolase and S-100, which presented intensive positive expressions. Dysphagia and Horner’s symptoms improved after surgery. There was no recurrence or metastases after 12 months.